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Proceedings Paper

Tomographic reconstruction of layered tissue structures
Author(s): Andreas H. Hielscher; Mohideen Azeez-Jan; Sebastian Bartel
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Paper Abstract

In recent years the interest in the determination of optical properties of layered tissue structure has resurfaced. Applications include, for example, studies on layered skin tissue and underlying muscles, imaging of the brain underneath layers of skin, skull, and meninges, and imaging of the fetal head in utero beneath the layered structures of the maternal abdomen. In this work we approach the problem of layered structures in the framework of model-based iterative image reconstruction schemes. These schemes are currently developed to determine the optical properties inside tissue from measurement on the surface. If applied to layered structure these techniques yield substantial improvements over currently available semi-analytical approaches.

Paper Details

Date Published: 2 November 2001
PDF: 8 pages
Proc. SPIE 4431, Photon Migration, Optical Coherence Tomography, and Microscopy, (2 November 2001); doi: 10.1117/12.447412
Show Author Affiliations
Andreas H. Hielscher, SUNY/Downstate Medical Ctr., and Polytechnic Univ. (United States)
Mohideen Azeez-Jan, SUNY/Downstate Medical Ctr. (United States)
Sebastian Bartel, Laser Zentrum Hannover e.V. (Germany)

Published in SPIE Proceedings Vol. 4431:
Photon Migration, Optical Coherence Tomography, and Microscopy
Stefan Andersson-Engels; Michael F. Kaschke, Editor(s)

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