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Proceedings Paper

Monte Carlo simulations and measurements of signals in laser Doppler flowmetry on human skin
Author(s): Marco H. Koelink; Frits F. M. de Mul; Jan Greve; Reindert Graaff; A. C. M. Dassel; Jan G. Aarnoudse
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Paper Abstract

Laser Doppler velocimetry provides a method for non invasive measurements of the perfusion of tissue. Therefore the tissue is illuminated with a monochromatic light source and back scattered light from the tissue is collected at a detector at an adjacent site. Some of the back scattered photons have had interaction with moving red blood cells and are frequency shifted. Due to interference of frequency shifted and non-frequency shifted photons the intensity at the detector fluctuates. These fluctuations provide the information from which a rate for the perfusion can be derived. In this paper we present perfusion measurements and Monte Carlo (MC) simulations on both a scale model and human skin tissue. The Monte Carlo results are used to quantify the size and position of the probe volume. Three different ways are presented to vary the size and position of the probe volume.

Paper Details

Date Published: 1 May 1991
PDF: 10 pages
Proc. SPIE 1431, Time-Resolved Spectroscopy and Imaging of Tissues, (1 May 1991); doi: 10.1117/12.44178
Show Author Affiliations
Marco H. Koelink, Univ. of Twente (Netherlands)
Frits F. M. de Mul, Univ. of Twente (Netherlands)
Jan Greve, Univ. of Twente (Netherlands)
Reindert Graaff, Univ. Hospital Groningen (Netherlands)
A. C. M. Dassel, Univ. Hospital Groningen (Netherlands)
Jan G. Aarnoudse, Univ. Hospital Groningen (Netherlands)

Published in SPIE Proceedings Vol. 1431:
Time-Resolved Spectroscopy and Imaging of Tissues
Britton Chance, Editor(s)

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