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Proceedings Paper

Clinical applications of L-lactate oxidase-based biosensor
Author(s): Keli Xing; Yanfan Liu; Lei Wang; Qiao Han; Lizhi Yin
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Paper Abstract

A L-lactate oxidase (LOD)-based biosensor is developed for the determination of L-lactate in blood samples. The L- lactate oxidase membrane is prepared by covalently linking LOD into a nylon set, followed by attaching the membrane onto a flow injection type of oxygen electrode. The response of the biosensor is based on the limited diffusion of L- lactate on the L-lactate oxidase membrane. No performance difference have been found between the LOD-based biosensor and regular enzyme optical determination methods for blood sample testing. It is suggested that the LOD-based biosensor may serve as an alternative for the detection of L-lactate in blood.

Paper Details

Date Published: 14 September 2001
PDF: 4 pages
Proc. SPIE 4414, International Conference on Sensor Technology (ISTC 2001), (14 September 2001); doi: 10.1117/12.440175
Show Author Affiliations
Keli Xing, Tianjin Medical Univ. (China)
Yanfan Liu, Tianjin Medical Univ. (China)
Lei Wang, Tianjin Medical Univ. (China)
Qiao Han, Tianjin Medical Univ. (China)
Lizhi Yin, Tianjin Medical Univ. (China)

Published in SPIE Proceedings Vol. 4414:
International Conference on Sensor Technology (ISTC 2001)
Yikai Zhou; Shunqing Xu, Editor(s)

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