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Proceedings Paper

Speckle diagnostics and biomicroscopy of lymph flow in microvessels
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Paper Abstract

In the present study speckle-interferometry and TV intravital biomicroscopy techniques has been proposed for the analysis of microcirculatory parameters. The power spectra of fluctuation of intensity, scattered by these vessels, have a complicated shape. The mean value of first spectral movement M1 (which is assumed to be directly proportional to average velocity) in lymphatics with spontaneous contractions differ from vessels without phasic activity. We register two types of histogram of M1 in contracting and non-contracting vessels. The phasic contractions may be caused by the modification of lymph flow in microvessels and/or by the changes of the speckle signal values. An application of lymphotropic drugs (staphylococcal toxin, N-nitro-L-arginine and dimethyl sufoxide) on the lymph microvessels has been investigated. The study of lymph flow by two methods (intravital TV biomicroscopy and speckle-interferometry) allows to determine the ways of the action of vasoactive drugs on lymph flow.

Paper Details

Date Published: 22 August 2001
PDF: 5 pages
Proc. SPIE 4427, Imaging of Tissue Structure and Function, (22 August 2001); doi: 10.1117/12.438416
Show Author Affiliations
Ekateryna I. Galanzha, Saratov State Univ. and Saratov State Medical Univ. (Russia)
Anastasiya V. Solov'eva, Saratov State Medical Univ. (Russia)
Sergey S. Ulyanov, Saratov State Univ. (Russia)
Valery V. Tuchin, Saratov State Univ. and Mechanical Engineering Institute (Russia)
Gregory E. Brill, Saratov State Medical Univ. (Russia)

Published in SPIE Proceedings Vol. 4427:
Imaging of Tissue Structure and Function
Valery V. Tuchin; Qingming Luo; Sergey S. Ulyanov, Editor(s)

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