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Proceedings Paper

Thermally induced birefringence changes in cartilage using polarization-sensitive optical coherence tomography
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Paper Abstract

Thermodynamic induced changes in birefringence of nasal septal cartilage following Nd:YAG laser irradiation were investigated using a polarization-sensitive optical coherence tomography (PSOCT) system. Birefringence in cartilage is due to the asymmetrical collagen fibril structure and may change if the underlying structure is disrupted due to local heat generation by absorption of laser radiation. A PSOCT instrument and an infrared imaging radiometer were used to record, respectively, depth-resolved images of the Stokes parameters of light backscattered from ex vivo porcine nasal septal cartilage and radiometric temperature following laser irradiation. PSOCT images of cartilage were recorded before (control), during, and after laser irradiation. From the measured Stokes parameters (I,Q,U, and V), an estimate of the relative phase retardation between two orthogonal polarizations was computed to determine birefringence in cartilage. Stokes parameter images of light backscattered from cartilage show significant changes due to laser irradiation. From our experiments we differentiate dehydration and thermal denaturation effects and observe the birefringence changes only in the dehydration effect. Therefore, a dynamic measurement of birefringence changes in cartilage using PSOCT as a feedback control methodology to monitor thermal denaturation is problematic in non-ablative surgical procedures such as laser assisted cartilage reshaping.

Paper Details

Date Published: 9 July 2001
PDF: 8 pages
Proc. SPIE 4257, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, (9 July 2001); doi: 10.1117/12.434742
Show Author Affiliations
Jong-In Youn, Univ. of Texas at Austin (United States)
Gracie Vargas, Univ. of Texas at Austin (United States)
Mathieu G. Ducros, Ecole Polytechnique Federale de Lausanne (Switzerland) (Switzerland)
Sergey A. Telenkov, Univ. of Texas at Austin (United States)
Brian Jet-Fei Wong M.D., Beckman Laser Institute and Medical Clinic (USA) and Univ. of California/Irvine (United States)
Thomas E. Milner, Univ. of Texas at Austin (United States)

Published in SPIE Proceedings Vol. 4257:
Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical
Donald Dean Duncan; Donald Dean Duncan; Steven L. Jacques; Peter C. Johnson; Peter C. Johnson, Editor(s)

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