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Proceedings Paper

Experimental tests of a two-layer Monte Carlo-diffusion hybrid model for photon migration in the frequency domain
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Paper Abstract

We examine the ability to recover the optical properties of a two-layer turbid medium using multi-distance frequency domain reflectance measurements and a hybrid Monte Carlo-- diffusion model. Frequency domain measurements are performed on two-layer liquid tissue phantoms simulating skin on muscle and skin on fat. Particular care to systematic effects in the photomultiplier is required for the measurements at short source-detectors distances. The model converges when fitting five free parameters (the optical properties of the upper and lower layers and the upper layer thickness). However, discrepancies between experimental and model yield insufficient accuracy for the absorption coefficient of the upper layer.

Paper Details

Date Published: 29 June 2001
PDF: 6 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434504
Show Author Affiliations
Gregory W. Faris, SRI International (United States)
George Alexandrakis, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
David R. Busch, SRI International (United States)
Michael S. Patterson, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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