Previous studies have suggested that the phased-array detection could achieve high sensitivity in detecting and localizing inhomogeneity embedded within turbid media by applying dual interfering sources. While the sensitivity of the phased array system will be influenced by various factors such as the source-detector configuration, the effect of noises (variation of source strength and phase, detector noise, imperfect homogeneous medium, etc.) and the modulation frequency. Analytical solutions as well as experimental data are presented to investigate the sensitivity of phased array detection using different degrees of absorption perturbation by varying the size and contrast of the absorber. Also we compare the result with the single source case under similar configuration. Different separations between two interfering sources have been compared to yield the maximum sensitivity for a typical perturbation. These results can be helpful for modifying the experimental apparatus to reach optimal detection sensitivity.

Date Published: 29 June 2001
PDF: 8 pages
Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001);

Published in SPIE Proceedings Vol. 4250:
Optical Tomography and Spectroscopy of Tissue IV
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)