We have designed a new optical probe to perform spatially resolved measurements of blood flow and oxygen consumption over an area of about 4 x 4 cm² of the lateral gastrocnemius muscle (calf muscle) of human subjects. The blood flow and the oxygen consumption were measured non- invasively with frequency-domain, near-infrared spectroscopy from the maximum rate of increase of the oxy- and deoxy- hemoglobin concentrations in the muscle during venous occlusion. In a preliminary test on one subject, involving measurements at rest and after exercise, we have found that the spatial variability of the measured blood flow and oxygen consumption is significantly greater than the variability of repeated measurements at a given tissue location. We have also observed a strong spatial dependence of the exercise-induced increase in blood flow and oxygen consumption.

Date Published: 4 May 2001
PDF: 9 pages
Proc. SPIE 4241, Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II, (4 May 2001); doi: 10.1117/12.431507

Published in SPIE Proceedings Vol. 4241:
Saratov Fall Meeting 2000: Optical Technologies in Biophysics and Medicine II
Valery V. Tuchin, Editor(s)