Share Email Print

Proceedings Paper

Segmentation of ulcerated plaque: evaluation and optimization of a semiautomatic method for tracking the progression of carotid atherosclerosis
Author(s): Jeremy D. Gill; Hanif M. Ladak; Aaron Fenster
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

A semi-automatic method for segmenting carotid lumen and plaque from three-dimensional vascular ultrasound (US) images has been developed. We examine its ability to distinguish changes in carotid vessel and plaque surface morphology, such as those caused by plaque ulceration. Two stenosed vessel phantoms were imaged using a 3D US imaging system. The phantoms were identical except for the inclusion of a hemispherical cut in the side of one of the vessels, in order to simulate the development of an ulceration. Ultrasound images of the phantoms were segmented using our algorithm, then the resulting surfaces were registered to one another using a rigid-body iterative closest point (ICP) algorithm. The volume of ulceration was determined by finding the difference between the two segmented surfaces in a region of interest surrounding the ulceration. Since the true volume of the ulceration was known a priori, an optimization strategy was used to tune the deformable model to better segment the ulceration. Analysis of ulceration volume as a function of the deformable model's parameters show that 1) large ulcerations are easily identified in our test case, and 2) the model is well behaved with respect to its parameters, suggesting that an automatic strategy for volumetric optimization is feasible.

Paper Details

Date Published: 3 July 2001
PDF: 10 pages
Proc. SPIE 4322, Medical Imaging 2001: Image Processing, (3 July 2001); doi: 10.1117/12.431014
Show Author Affiliations
Jeremy D. Gill, John P. Robarts Research Institute and Univ. of Western Ontario (Canada)
Hanif M. Ladak, John P. Robarts Research Institute and Univ. of Western Ontario (Canada)
Aaron Fenster, John P. Robarts Research Institute and Univ. of Western Ontario (Canada)

Published in SPIE Proceedings Vol. 4322:
Medical Imaging 2001: Image Processing
Milan Sonka; Kenneth M. Hanson, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?