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Proceedings Paper

Breast cancer diagnosis using scattered x rays?
Author(s): Robert A. Lewis; Keith D. Rogers; Christopher J. Hall; Andrew Evans; Sarah E. Pinder; Ian O. Ellis; Alan P. Hufton; Elizabeth Towns-Andrews; Susan Slawson; David R. Dance; Caroline R. M. Boggis
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Paper Abstract

We have performed small angle X-ray scattering measurements at the Synchrotron Radiation Source at Daresbury to make an initial assessment of the diagnostic information obtainable from various breast tissues. These experiments have indicated that high quality interpretable diffraction data can be rapidly produced from breast core cut biopsy specimens. We have demonstrated a remarkable and systematic difference between the X-ray scattering from normal, benign and malignant breast tissue collagen. Our findings indicate that it may be possible to use molecular structure characteristics of breast tissue as novel markers of disease progression.

Paper Details

Date Published: 28 June 2001
PDF: 8 pages
Proc. SPIE 4320, Medical Imaging 2001: Physics of Medical Imaging, (28 June 2001); doi: 10.1117/12.430877
Show Author Affiliations
Robert A. Lewis, Daresbury Lab. (United Kingdom)
Keith D. Rogers, Cranfield Univ. (United Kingdom)
Christopher J. Hall, Daresbury Lab. (United Kingdom)
Andrew Evans, City Hospital Nottingham (United Kingdom)
Sarah E. Pinder, City Hospital Nottingham (United Kingdom)
Ian O. Ellis, City Hospital Nottingham (United Kingdom)
Alan P. Hufton, Christie Hospital (United Kingdom)
Elizabeth Towns-Andrews, Daresbury Lab. (United Kingdom)
Susan Slawson, Daresbury Lab. (United Kingdom)
David R. Dance, Royal Marsden Hospital (United Kingdom)
Caroline R. M. Boggis, Withington Hospital (United Kingdom)

Published in SPIE Proceedings Vol. 4320:
Medical Imaging 2001: Physics of Medical Imaging
Larry E. Antonuk; Martin Joel Yaffe, Editor(s)

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