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Proceedings Paper

Erbium:YAG laser ablation of urethral and ureteral tissues
Author(s): Nathaniel M. Fried; Gary M. Long Jr.
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Paper Abstract

Cold knife incision of urological strictures results in a high rate of stricture recurrence. This study compares Ho:YAG and Er:YAG lasers for precise incision of urethral and ureteral tissues. Laser ablation was performed using Ho:YAG (?=2.1 µm) and Er:YAG (?=2.94 µm) lasers operating in long-pulse mode (?p = 300 µs). Ho:YAG laser radiation was delivered through low-OH fibers while Er:YAG laser radiation was delivered through germanium oxide or sapphire fibers. Ex vivo canine and porcine tissue samples were placed in saline, and perforation thresholds, ablation rates, and histological thermal damage measurements were recorded. Optical fiber damage thresholds during contact ablation were also studied. The Ho:YAG and Er:YAG lasers perforated thick tissue samples at thresholds of 350 J/cm2 and 65 J/cm2, respectively, with peripheral thermal damage zones measuring 290 + 30 µm and 30 + 10 µm, respectively. Germanium oxide fibers were damaged at energies greater than 150 mJ/pulse (80 JIcm2), but no damage to sapphire fibers was observed at energies up to 450 mJ/pulse (3 50 J/cm2). The Er:YAG laser efficiently ablates urethral and ureteral tissues while reducing peripheral thermal damage by an order of magnitude over the Ho:YAG laser. In vivo animal studies for Er:YAG laser incision of strictures are planned with comparison to cold knife incision.

Paper Details

Date Published: 17 June 2002
PDF: 6 pages
Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); doi: 10.1117/12.430657
Show Author Affiliations
Gary M. Long Jr.

Published in SPIE Proceedings Vol. 4609:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII
Lawrence S. Bass M.D.; Eugene A. Trowers M.D.; Kenneth Eugene Bartels D.V.M.; Udayan K. Shah M.D.; David S. Robinson M.D.; Lawrence S. Bass M.D.; Kenton W. Gregory M.D.; Kenneth Eugene Bartels D.V.M.; Lawrence S. Bass M.D.; Brian Jet-Fei Wong M.D.; Hans-Dieter Reidenbach; Lloyd P. Tate V.D.M.; Nikiforos Kollias; Abraham Katzir; Timothy A. Woodward M.D.; Werner T.W. de Riese; George M. Peavy D.V.M.; Werner T.W. de Riese; Kenton W. Gregory M.D.; Michael D. Lucroy D.V.M.; Abraham Katzir; Nikiforos Kollias; Michael D. Lucroy D.V.M.; Reza S. Malek M.D.; George M. Peavy; Hans-Dieter Reidenbach; David S. Robinson M.D.; Udayan K. Shah M.D.; Lloyd P. Tate V.D.M.; Eugene A. Trowers M.D.; Brian Jet-Fei Wong M.D.; Timothy A. Woodward M.D., Editor(s)

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