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Proceedings Paper

Proposed system for ultrasonic temperature imaging of the human prostate in vivo during transurethral microwave thermotherapy: data acquisition and initial experience
Author(s): Aswin L. Hoffmann; Jean J.M.C.H. de la Rosette; Hessel Wijkstra
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Paper Abstract

The feasibility of using a minimally-invasive pulse-echo diagnostic ultrasound technique for estimation of the spatiotemporal temperature distribution in the human prostate in vivo during transurethral microwave thermotherapy (TUMT) was investigated. The tissue temperature distribution was estimated using a method which allows spatially resolved measurement of changes in time of flight. Backscattered ultrasound RF signals were acquired from a commercially-available 7.5 MHz transrectal imaging probe and processed to compute and image the apparent tissue internal displacement distribution. The temperature distribution was determined by exploiting an estimated initial sound speed distribution and an empirical relationship between temperature and ultrasound transmission speed. Results form an in-vitro phantom study showed a linear relationship between induced displacement and temperature for a limited temperature range. Initial results from an exploratory in-vivo study in patients undergoing TUMT showed substantial influence form tissue motion and deformation. Problems inherent to in-vivo data acquisition are discussed and potential solutions are proposed. Possible approaches to further improve the algorithm and to assess the ability of the system to estimate and monitor the intraprostatic temperature distribution during TUMT are presented.

Paper Details

Date Published: 30 May 2001
PDF: 12 pages
Proc. SPIE 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing, (30 May 2001); doi: 10.1117/12.428240
Show Author Affiliations
Aswin L. Hoffmann, Univ. Medical Ctr. Nijmegen (Netherlands)
Jean J.M.C.H. de la Rosette, Univ. Medical Ctr. Nijmegen (Netherlands)
Hessel Wijkstra, Univ. Medical Ctr. Nijmegen (Netherlands)

Published in SPIE Proceedings Vol. 4325:
Medical Imaging 2001: Ultrasonic Imaging and Signal Processing
Michael F. Insana; K. Kirk Shung, Editor(s)

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