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Proceedings Paper

Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom
Author(s): Tracy L. Faber; Ernest V. Garcia; David S. Lalush; W. Paul Segars; Benjamin M.W. Tsui
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Paper Abstract

The spline-based Mathematical Cardiac Torso (MCAT) phantom is a realistic software simulation designed to simulate single photon emission computed tomographic (SPECT) data. It incorporates a heart model of known size and shape; thus, it is invaluable for measuring accuracy of acquisition, reconstruction, and post-processing routines. New functionality has been added by replacing the standard heart model with left ventricular (LV) epicaridal and endocardial surface points detected from actual patient SPECT perfusion studies. LV surfaces detected from standard post-processing quantitation programs are converted through interpolation in space and time into new B-spline models. Perfusion abnormalities are added to the model based on results of standard perfusion quantification. The new LV is translated and rotated to fit within existing atria and right ventricular models, which are scaled based on the size of the LV. Simulations were created for five different patients with myocardial infractions who had undergone SPECT perfusion imaging. Shape, size, and motion of the resulting activity map were compared visually to the original SPECT images. In all cases, size, shape and motion of simulated LVs matched well with the original images. Thus, realistic simulations with known physiologic and functional parameters can be created for evaluating efficacy of processing algorithms.

Paper Details

Date Published: 28 May 2001
PDF: 5 pages
Proc. SPIE 4319, Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures, (28 May 2001); doi: 10.1117/12.428050
Show Author Affiliations
Tracy L. Faber, Emory Univ. (United States)
Ernest V. Garcia, Emory Univ. (United States)
David S. Lalush, Univ. of North Carolina/Chapel Hill (United States)
W. Paul Segars, Univ. of North Carolina/Chapel Hill (United States)
Benjamin M.W. Tsui, Univ. of North Carolina/Chapel Hill (United States)

Published in SPIE Proceedings Vol. 4319:
Medical Imaging 2001: Visualization, Display, and Image-Guided Procedures
Seong Ki Mun, Editor(s)

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