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Proceedings Paper

Normalization and error estimation for biomedical expression patterns
Author(s): Stanley D. Luck
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Paper Abstract

We describe methods for the analysis expression patterns based on a vector representation for intensities. Normalization for multiple experiments is iterative and is obtained by identifying a vector that optimally correlates expression patterns. Error estimates for intensities are obtained by analyzing deviations in expression relative to the correlation vector. A normalization method for applying corrections from spiked, two-color fluorescence measurements is also described.

Paper Details

Date Published: 4 June 2001
PDF: 5 pages
Proc. SPIE 4266, Microarrays: Optical Technologies and Informatics, (4 June 2001); doi: 10.1117/12.427984
Show Author Affiliations
Stanley D. Luck, DuPont Biotechnology-Agricultural Genomics (United States)

Published in SPIE Proceedings Vol. 4266:
Microarrays: Optical Technologies and Informatics
Michael L. Bittner; Yidong Chen; Andreas N. Dorsel; Edward R. Dougherty, Editor(s)

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