Self-assembled monolayers (SAMs) of alkanthiols have been studied and applied to enzyme modification on metal electrode. The construction of enzyme electrode using SAM is one of the considerable approaches for enzyme sensors. Glucose electrode and lactate electrode were fabricated on gold electrode by alkanthiols. The electrode response allowed to differentiate between long and short alkyl chains of alkanthiols. This result suggests that SAM with different chain length change their surface properties and affect electrochemical response of enzyme modified electrodes. On the basis of the result, micro machined glucose electrode was fabricated and its response was measured.

Date Published: 21 May 2001
PDF: 6 pages
Proc. SPIE 4265, Biomedical Instrumentation Based on Micro- and Nanotechnology, (21 May 2001); doi: 10.1117/12.427970

Published in SPIE Proceedings Vol. 4265:
Biomedical Instrumentation Based on Micro- and Nanotechnology
Raymond P. Mariella Jr.; Dan V. Nicolau, Editor(s)