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Proceedings Paper

IDTT therapy in cadaveric lumbar spine: temperature and thermal dose distributions
Author(s): Chris J. Diederich; William H. Nau; Frank Kleinstueck; Jeff Lotz; David Bradford
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Paper Abstract

The purpose of this study was to perform extensive temperature mapping throughout human cadaveric disc (n=12) specimens during Intradiscal Thermal Therapy IDTT using the SpineCathTM applicator. Temperature distributions and accumulated thermal dose or thermal damage calculated from the temperature-time history are used to define probable regions of thermal necrosis (destruction of nerves) or thermal coagulation (induced structural changes). The IDTT procedure using SpineCath (5 cm resistive heating segment) and the current standard heating protocol (~17 min) produces intra-discal temperatures which are too low to generate appreciable regions of thermal coagulation and resultant changes in biomechanical properties. This finding was supported by temperature measurements which were mostly below the critical temperature of 60-65°C, except for regions within 1-2 mm of the SpineCath applicator. Furthermore, the analysis of the thermal dose profiles indicate that sufficient thermal doses (240-640 EM43°C) capable of generating complete thermal damage to the nociceptive nerves fibers infiltrating the disc are limited to within ~6 mm of the nucleus and IDTT probe heating segment.

Paper Details

Date Published: 1 June 2001
PDF: 5 pages
Proc. SPIE 4247, Thermal Treatment of Tissue: Energy Delivery and Assessment, (1 June 2001); doi: 10.1117/12.427849
Show Author Affiliations
Chris J. Diederich, Univ. of California/San Francisco (United States)
William H. Nau, Univ. of California/San Francisco (United States)
Frank Kleinstueck, Univ. of California/San Francisco (United States)
Jeff Lotz, Univ. of California/San Francisco (United States)
David Bradford, Univ. of California/San Francisco (United States)

Published in SPIE Proceedings Vol. 4247:
Thermal Treatment of Tissue: Energy Delivery and Assessment
Thomas P. Ryan, Editor(s)

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