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Proceedings Paper

Dynamic tether force measurements of the outer hair cells plasma membrane with optical tweezers
Author(s): Bahman Anvari; Zhiwei Li; Masayoshi Takashima; Peter Brecht; Jorge H. Torres M.D.; William E. Brownell
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Paper Abstract

The mechanical characteristics of the outer hair cells (OHCs) plasma membrane was studied by forming tethers with optical tweezers. The average force to and from a plasma membrane tether at the lateral wall of the OHC was about 3.5 times greater than that at the basal end of the cell, consistent with the presence of a more extensive cytoskeleton support beneath the PM at the site of the lateral wall. The apparent viscosity of the PM was measured by pulling tethers at different rates while continuously recording the tether force, and was estimated in the range of 13-33 pN*s/micrometers .

Paper Details

Date Published: 10 May 2001
PDF: 6 pages
Proc. SPIE 4260, Optical Diagnostics of Living Cells IV, (10 May 2001); doi: 10.1117/12.426765
Show Author Affiliations
Bahman Anvari, Rice Univ. (United States)
Zhiwei Li, Rice Univ. (United States)
Masayoshi Takashima, Baylor College of Medicine (United States)
Peter Brecht, Rice Univ. (United States)
Jorge H. Torres M.D., Rice Univ. (United States)
William E. Brownell, Baylor College of Medicine (United States)


Published in SPIE Proceedings Vol. 4260:
Optical Diagnostics of Living Cells IV
Daniel L. Farkas; Robert C. Leif; Robert C. Leif, Editor(s)

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