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Proceedings Paper

Comparison of adhesive markers, anatomical landmarks, and surface matching in patient-to-image registration for frameless stereotaxy
Author(s): Peter W. A. Willems; Jan Willem Berkelbach van der Sprenkel; Cees A. F. Tulleken M.D.
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Paper Abstract

The application accuracy of frameless stereotaxy depends partly on the accuracy of the patient-to-image registration procedure. We compared the application accuracy of registration procedures based on anatomical landmarks, surface matching, and adhesive markers. After acquisition of a 3D-MRI volume, 30 patients were subjected to all three registration procedures. Frameless stereotaxy was performed with the STN system (Carl Zeiss, Germany). Following each registration procedure, the root-mean-squared-error (RMSE) and the target registration error (TRE) of an extra adhesive marker (target) were recorded. The first represents the goodness-of-fit of the registration procedure (not available in surface matching) while the second represents the application accuracy. The mean TRE+/- SD for each type of registration was 5.3+/- 2.1mm, 9.4+/- 6.6mm, and 3.6+/- 1.6mm (paired t-tests: p<0.01). When anatomical landmarks were used, anterior targets generated smaller TREs than posterior targets (4.6+/- 2.0mm and 6.8+/- 1.3mm respectively, t-test: p<0.01). There was no significant correlation between the RMSE and the TRE (anatomical landmarks: R2=0.071, adhesive markers: R2=0.004). A more detailed evaluation of surface matching, using a plastic skull phantom, also could not demonstrate an improvement in application accuracy due to surface matching. In conclusion, our results indicate that adhesive markers offer the most accurate alternative to bonescrews. However, we believe anatomical landmarks to provide sufficient accuracy for many neurosurgical procedures concerning frontally located targets, reducing the need for extra preoperative imaging.

Paper Details

Date Published: 19 January 2001
PDF: 8 pages
Proc. SPIE 4158, Biomonitoring and Endoscopy Technologies, (19 January 2001); doi: 10.1117/12.413791
Show Author Affiliations
Peter W. A. Willems, Univ. Medical Ctr. Utrecht (Netherlands)
Jan Willem Berkelbach van der Sprenkel, Univ. Medical Ctr. Utrecht (Netherlands)
Cees A. F. Tulleken M.D., Univ. Medical Ctr. Utrecht (Netherlands)

Published in SPIE Proceedings Vol. 4158:
Biomonitoring and Endoscopy Technologies
Israel Gannot; Yuri V. Gulyaev; Theodore G. Papazoglou; Christiaan F. P. van Swol, Editor(s)

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