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Proceedings Paper

Novel photosensitizers for prospective clinical usage and some of their properties
Author(s): Andrei V. Reshetnickov; Stefan B. Spaniol; N. P. Neugodova; G. A. Sapozhnikova; Olga Yu. Abakumova; Tatyana A. Tsvetkova; Igor Dmitrievich Zalevsky; S. E. Goncharov; Artashes V. Karmenyan; Gelii V. Ponomarev
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Paper Abstract

Five novel photosensitizers for photodynamic tumor therapy have been offered as potential drug substances for the prospective clinical usage. A complex of pre-clinic biological studies has been performed, unambiguously demonstrating low systemic toxicity and high photodynamic potential of the substances proposed. The one named 'Photodithazine/Photochlorin I' has already successfully passed a number of clinical test on patients having immergent vital indications.

Paper Details

Date Published: 31 January 2001
PDF: 5 pages
Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); doi: 10.1117/12.413699
Show Author Affiliations
Andrei V. Reshetnickov, Institute of Biomedical Chemistry (Russia)
Stefan B. Spaniol, BioLitec AG (Germany)
N. P. Neugodova, Institute for State Control of Medicinal Drugs (Russia)
G. A. Sapozhnikova, Institute for State Control of Medicinal Drugs (Russia)
Olga Yu. Abakumova, Institute of Biomedical Chemistry (Russia)
Tatyana A. Tsvetkova, Institute of Biomedical Chemistry (Russia)
Igor Dmitrievich Zalevsky, Sigma Plus Co. (Russia)
S. E. Goncharov, Sigma Plus Co. (Russia)
Artashes V. Karmenyan, N.N. Blokhin Cancer Research Ctr. (Russia)
Gelii V. Ponomarev, Institute of Biomedical Chemistry (Russia)

Published in SPIE Proceedings Vol. 4156:
Clinical Lasers and Diagnostics
Patrick Brouwer, Editor(s)

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