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Proceedings Paper

Mathematical modeling and fiber optics parameter optimization in diagnostics of biotissue by PNC method
Author(s): Alexander A. Sokolovsky; Victor I. Masychev
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Paper Abstract

Optical PNC-diagnostics is one of the methods to diagnose biotissue in norm and pathology. In primary case backscattering and fluorescent components of detected secondary radiations are registered by means of PNC-method. These radiations are stimulated and occur when probing laser beam radiates biotissue. For diagnostic purposes both monofibers and multifiber probes (fiber bundle), where probing radiation transmits to biotissue via one of the fibers, are usually used. Registered secondary radiations from biotissue are detected by distal end of a multifiber probe (peripheral fibers). This work was intended to mathematically modulate and determine optimization parameters of fiberoptic probes, applied in PNC-diagnostics inclusive localization and depth of pathological underskin hearth. Main mathematical correlations and formulas for calculation and optimization of backscattering radiation in dependence on applied waveguide characteristics inclusive radiation absorption in biotissue were obtained. All calculations are made regarding each biotissue layer as reflective or Lambert quasi-source of backscattering signal. It is found out, that varying parameters in a probe we can vary the depth of tissue where the maximum signal received from and optimize the value of the signal.

Paper Details

Date Published: 11 October 2000
PDF: 7 pages
Proc. SPIE 4224, Biomedical Photonics and Optoelectronic Imaging, (11 October 2000); doi: 10.1117/12.403946
Show Author Affiliations
Alexander A. Sokolovsky, Rosslyn Medical UK/Moscow Office (Russia)
Victor I. Masychev, Rosslyn Medical UK/Moscow Office (Russia)

Published in SPIE Proceedings Vol. 4224:
Biomedical Photonics and Optoelectronic Imaging
Hong Liu; Qingming Luo, Editor(s)

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