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Proceedings Paper

Diagnosis and prognosis of tissue pathologies by Raman microspectroscopy: an application to human thyroid tumors
Author(s): Michel Manfait; Philippe Lamaze; Hasnae Lamfarraj; Michel Pluot; Ganesh D. Sockalingum
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Paper Abstract

This study shows a first application of Raman microspectroscopy to the study of thyroid tissue samples classified as carcinomas, adenomas and nodules. Treatment of the Raman data using statistical methods show that it is possible to classify most of the samples in accord with the pathological examinations. Furthermore, Raman spectral image based on specific bands or frequencies defined as 'functional descriptors' allow to construct maps of micro- zones of such tissues. Such maps can be useful as complementary tools for tissue diagnosis and prognosis, since they carry molecular information important to such ends.

Paper Details

Date Published: 8 May 2000
PDF: 8 pages
Proc. SPIE 3918, Biomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques, (8 May 2000); doi: 10.1117/12.384936
Show Author Affiliations
Michel Manfait, Univ. de Reims Champagne-Ardenne (France)
Philippe Lamaze, Univ. de Reims Champagne-Ardenne (France)
Hasnae Lamfarraj, Univ. de Reims Champagne-Ardenne (France)
Michel Pluot, Centrale Hospitalier Univ. de Reims (France)
Ganesh D. Sockalingum, Univ. de Reims Champagne-Ardenne (France)

Published in SPIE Proceedings Vol. 3918:
Biomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques
Anita Mahadevan-Jansen; Gerwin J. Puppels, Editor(s)

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