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Proceedings Paper

Spatially varying detectability for optical tomography
Author(s): Angel R. Pineda; Harrison H. Barrett; Simon Robert Arridge
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Paper Abstract

We apply task-based assessment of image quality to optical tomography imaging systems. In particular, we studied the task of detecting a signal, specified as a change in scattering and absorption coefficients, when its shape and location were known. The detectability was quantified using the optimal linear (Hotelling) observer. The non-linearity of the problem was no impediment in computing the Hotelling observer using a hybrid approach that combines knowledge of the measurement statistics with sampling to account for anatomical variation. We compared the observer performance on the raw data in uniform and structured backgrounds for several data and signal types. Two of the data types studied were the total number of photons (total counts) collected for each source-detector pair and their respective mean time of arrival. Results show that the spatial variation of detectability was different for the total counts than for the mean time. The performance of the total counts and its relative performance to the mean time varied significantly with both signal type and background variations.

Paper Details

Date Published: 25 April 2000
PDF: 7 pages
Proc. SPIE 3977, Medical Imaging 2000: Physics of Medical Imaging, (25 April 2000); doi: 10.1117/12.384548
Show Author Affiliations
Angel R. Pineda, Univ. of Arizona (United States)
Harrison H. Barrett, Univ. of Arizona and Optical Sciences Ctr./Univ. of Arizona (United States)
Simon Robert Arridge, Univ. College London (United Kingdom)

Published in SPIE Proceedings Vol. 3977:
Medical Imaging 2000: Physics of Medical Imaging
James T. Dobbins III; John M. Boone, Editor(s)

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