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Proceedings Paper

High-throughput pharmocology system HT-PS 100: instrument for automated quantitative analysis of a ligand-receptor interaction based on ligand concentration-dependent functional responses in cells
Author(s): Ilya Okun; Gregory V. Kaler; Michael Otto; Alex Okun
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Paper Abstract

Contrary to conventionally used serial discrete dilutions of a ligand to construct concentration-response curves with a few experimental points, we describe here an automated system, HT-PSTM 100, that produces continuous ligand concentration gradients for interrogating cells in flow, and concurrently measures the ligand-induced functional response.

Paper Details

Date Published: 26 April 2000
PDF: 8 pages
Proc. SPIE 3924, Molecular Imaging: Reporters, Dyes, Markers, and Instrumentation, (26 April 2000); doi: 10.1117/12.384244
Show Author Affiliations
Ilya Okun, AXIOM Biotechnologies, Inc. (United States)
Gregory V. Kaler, AXIOM Biotechnologies, Inc. (United States)
Michael Otto, AXIOM Biotechnologies, Inc. (United States)
Alex Okun, AXIOM Biotechnologies, Inc. (United States)

Published in SPIE Proceedings Vol. 3924:
Molecular Imaging: Reporters, Dyes, Markers, and Instrumentation
Darryl J. Bornhop; Kai Licha, Editor(s)

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