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Proceedings Paper

Laser-induced fluorescence spectrum of human colonic tissues by Monte Carlo modeling
Author(s): Zhiwei Huang; Teck-Chee Chia; Sing Lee; Wei Zheng; Sanjay M. Krishnan; Tuan-Kay Lim; Horn Mun Cheah; Cheong Hoong Diong; Francis Seow Choen
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Paper Abstract

Based on the microscopic properties of colonic tissues, a five-layer colon optical model was developed to calculate the excitation light distribution in the tissue and the fluorescence escape function from the tissue by Monte Carlo simulations. The theoretically modeled fluorescence spectrum fits well to the experimental results, demonstrating that the microscopic properties of tissue applied in the colon optical model can be quantitatively correlated with the macroscopic autofluorescence measurements.

Paper Details

Date Published: 19 April 2000
PDF: 7 pages
Proc. SPIE 3917, Optical Biopsy III, (19 April 2000); doi: 10.1117/12.382726
Show Author Affiliations
Zhiwei Huang, Nanyang Technological Univ. (Canada)
Teck-Chee Chia, Nanyang Technological Univ. (Singapore)
Sing Lee, Nanyang Technological Univ. (Singapore)
Wei Zheng, Nanyang Technological Univ. (Singapore)
Sanjay M. Krishnan, Nanyang Technological Univ. (Singapore)
Tuan-Kay Lim, Nanyang Technological Univ. (Singapore)
Horn Mun Cheah, Nanyang Technological Univ. (Singapore)
Cheong Hoong Diong, Nanyang Technological Univ. (Singapore)
Francis Seow Choen, Singapore General Hospital (Singapore)

Published in SPIE Proceedings Vol. 3917:
Optical Biopsy III
Robert R. Alfano, Editor(s)

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