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Proceedings Paper

Optical biopsy with long-range nondiffracting beams
Author(s): Ervin Goldfain
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Paper Abstract

Most current configurations for optical biopsy contain fiber optic bundles at both the delivery and receiving ends of the optical system. Some layouts include distal lenses to either collimate or focus the incident light at various depth locations across the tissue. The inherent beam divergence, along with the highly scattering nature of the living tissue, are known to limit the penetration depth of the probe and the spatial or temporal resolution of the detected signal. In this work we study a novel modality for tissue illumination based on the use of long-range nondiffracting beams (LRNB). LRNB represent narrow-width light pencils with a constant or linearly varying axial intensity that propagate over large distances without diffractive spreading. Recent tests have demonstrated that LRNB exhibit in significant intensity distortions when operated as beacon beams through atmospheric turbulence. Our numerical and software simulations show that LRNB may offer the potential for larger penetration depth and enhanced contrast over setups using conventional laser beams. Clinical applications include diagnosis, laser surgery and photodynamic therapy.

Paper Details

Date Published: 19 April 2000
PDF: 9 pages
Proc. SPIE 3917, Optical Biopsy III, (19 April 2000); doi: 10.1117/12.382723
Show Author Affiliations
Ervin Goldfain, Welch Allyn, Inc. (United States)

Published in SPIE Proceedings Vol. 3917:
Optical Biopsy III
Robert R. Alfano, Editor(s)

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