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Proceedings Paper

Scattering of polarized light by biological tissues
Author(s): Steven L. Jacques; Kenneth Lee M.D.; Jessica C. Ramella-Roman
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Paper Abstract

Polarized light can be used to obtain images of superficial tissue layers such as skin and some examples images are presented. This paper present a study of the transition of linearly polarized light into randomly polarized light during light propagation through tissues. The transition of polarization was studied in polystyrene microsphere solutions and in chicken muscle and liver. The transition is discussed in terms of a diffusion process characterized by an angular diffusivity for the change in angular orientation of linearly polarized light per unit optical path traveled by the light. The results are consistent with the hypothesis that birefringent tissues randomize linearly polarized light more rapidly than nonbirefringent tissues. The results suggest that polarized light imagin of skin tissues based only on photons backscattered from the superficial epidermal and initial papillary dermis because the birefringent dermal collagen rapidly randomizes polarized light. This anatomical region of the skin is where cancer commonly arises.

Paper Details

Date Published: 6 April 2000
PDF: 15 pages
Proc. SPIE 4001, Saratov Fall Meeting '99: Optical Technologies in Biophysics and Medicine, (6 April 2000); doi: 10.1117/12.381506
Show Author Affiliations
Steven L. Jacques, Oregon Medical Laser Ctr. Providence St. Vincent Medical Ctr. (United States)
Kenneth Lee M.D., Oregon Health Sciences Univ. (United States)
Jessica C. Ramella-Roman, Oregon Graduate Institute (United States)

Published in SPIE Proceedings Vol. 4001:
Saratov Fall Meeting '99: Optical Technologies in Biophysics and Medicine
Valery V. Tuchin; Dmitry A. Zimnyakov; Alexander B. Pravdin, Editor(s)

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