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Proceedings Paper

Laser correlation spectrometry: a new approach to organizing oncological screening for a population exposed to chronic irradiation
Author(s): Alexander Akleyev; Igor Pashkov; Mikhail Kisselyov; Leonid A. Noskin
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Paper Abstract

The issue of stochastic effects of radiation exposure (mostly leukemia and cancer), and early detection of malignant tumors, as a key aspect of the problem, is of crucial importance to the population chronically exposed due to the activities of the Mayak Production Association in the Urals region (Russia). Given the large number of exposed population, screening is considered to be the most expedient method to organize medical observation of exposed persons. As was shown by the results of medical examinations conducted for 1 391 residents of the Techa riverside villages, laser correlation spectrometry (LCS) of blood plasma has proved to be a highly effective screening method for early (pre-clinical) detection of malignant neoplasms and pre-cancerous conditions. It was established that LC- spectra of blood plasma in persons with cancer and pre- cancer can easily be differentiated from non-cancer conditions. Of particular diagnostic significance is the high-frequency range of the spectrum. The development of a diagnostic algorithm has allowed to carry out a computer- based classification of blood plasma LC spectra as a component of exposed population health monitoring system.

Paper Details

Date Published: 30 December 1999
PDF: 11 pages
Proc. SPIE 4059, Laser Use in Oncology II, (30 December 1999); doi: 10.1117/12.375274
Show Author Affiliations
Alexander Akleyev, Urals Research Ctr. for Radiation Medicine (Russia)
Igor Pashkov, Urals Research Ctr. for Radiation Medicine (Russia)
Mikhail Kisselyov, Federal Agency Medbioextrem (Russia)
Leonid A. Noskin, St. Petersburg Institute for Nuclear Physics (Russia)

Published in SPIE Proceedings Vol. 4059:
Laser Use in Oncology II
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

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