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Proceedings Paper

Alteration of photosensitizer content and parameters of free radical reactions in a patient's blood under photodynamic therapy of malignant tumors
Author(s): G. N. Lubchenko; Tatyana V. Chichuk; Eugeny Ph. Stranadko
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Paper Abstract

The purpose of this study was to determine the changes in concentrations of the two Russian photosensitizers in blood plasma of patients under Photodynamic therapy. In this work were used two sensitizers of domestic production: Photohem (hematoporphyrin derivative) and Photosense (sulfonated aluminium phtalocyanine). It was found that one month after injection the concentrations of the photosensitizers in blood plasma remained high enough. Was shown alteration of level of apo-(beta) -lipoproteins oxidation and antioxidant activity of blood plasma under the influence of Photodynamic therapy.

Paper Details

Date Published: 30 December 1999
PDF: 7 pages
Proc. SPIE 4059, Laser Use in Oncology II, (30 December 1999); doi: 10.1117/12.375261
Show Author Affiliations
G. N. Lubchenko, State Scientific Ctr. for Laser Medicine (Russia)
Tatyana V. Chichuk, State Scientific Ctr. for Laser Medicine (Russia)
Eugeny Ph. Stranadko, State Scientific Ctr. for Laser Medicine (Russia)

Published in SPIE Proceedings Vol. 4059:
Laser Use in Oncology II
Andrei V. Ivanov; Mishik A. Kazaryan, Editor(s)

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