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Proceedings Paper • Open Access

Magnetic resonance techniques for real-time assessment of thermal treatment
Author(s): Thaddeus V. Samulski

Paper Abstract

This paper reviews the application of MRI as a non-invasive technique for accessing temperature in thermal therapies. Two MR parameters, T1 relaxation and proton resonance frequency (PRF), have shown temperature sensitivity that is measurable with MRI. A third temperature dependent parameter associated with the self-diffusion of water, referred to as the apparent diffusion coefficient (ADC), is not intrinsic to nuclear magnetic resonance (NMR), but can be measured using MRI. These three parameters have been useful for quantitatively mapping temperature distributions in vivo. Each requires a tailored imaging technique. Each has pros and cons with regard to a given application. At this point in the development of MR image guided temperature mapping, the PRF shift technique is preferable, particularly with regard to non-invasive thermal ablation procedures. This approach has problems with stability and motion in procedures that require heating for extended time periods. Further development of MRI thermometry is required for long duration procedures.

Paper Details

Date Published: 24 January 2000
PDF: 20 pages
Proc. SPIE 10297, Matching the Energy Source to the Clinical Need: A Critical Review, 102970G (24 January 2000); doi: 10.1117/12.375217
Show Author Affiliations
Thaddeus V. Samulski, Duke Univ. Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 10297:
Matching the Energy Source to the Clinical Need: A Critical Review
Thomas P. Ryan, Editor(s)

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