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Proceedings Paper

Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline
Author(s): Pam S. Bromberg; Kathleen M. Gough; Mandy Ogg; M. R. Del Bigio; Robert Julian
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Paper Abstract

Alzheimer's Disease is a neurodegenerative disorder marked by progressive cognitive decline. AD presents with many of the same clinical symptoms as senile dementia, but the diagnosis of AD must be confirmed by post-mortem examination of the morphological and histopathological features of the brain. The two classical lesions found in the cortical and hippocampal regions of the brain are the (beta) -amyloid- bearing neuritic plaques and the intraneuronal neurofibrillary tangles.

Paper Details

Date Published: 25 October 1999
PDF: 9 pages
Proc. SPIE 3775, Accelerator-based Sources of Infrared and Spectroscopic Applications, (25 October 1999); doi: 10.1117/12.366636
Show Author Affiliations
Pam S. Bromberg, Univ. of Manitoba (Canada)
Kathleen M. Gough, Univ. of Manitoba (Canada)
Mandy Ogg, Univ. of Manitoba (Canada)
M. R. Del Bigio, Univ. of Manitoba (Canada)
Robert Julian, Univ. of Wisconsin/Madison (United States)

Published in SPIE Proceedings Vol. 3775:
Accelerator-based Sources of Infrared and Spectroscopic Applications
G. Lawrence Carr; Paul Dumas, Editor(s)

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