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Proceedings Paper

New supramolecular system binding to nucleic acids
Author(s): Xue-Mei Wang; Lintao Cai
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Paper Abstract

The potential of some novel dansylamide derivatives to complex with polynucleotides in aqueous solution has been investigated primarily by absorption, circular dichroism and fluorescence spectroscopy. The results indicate that these spectroscopies are strongly affected upon complexation, which may be contributed to the stacking interactions of the aromatic units, specific electronic interaction, and/or conformational changes of host- guest system. Besides, the nanostructural images of the complexes by atomic force microscopy also provide fresh direct evidence for the relationship between the structures of supramolecules and the relative conformational changes of nucleic acids.

Paper Details

Date Published: 17 September 1999
PDF: 7 pages
Proc. SPIE 3863, 1999 International Conference on Biomedical Optics, (17 September 1999); doi: 10.1117/12.364380
Show Author Affiliations
Xue-Mei Wang, Southeast Univ. (China)
Lintao Cai, Southeast Univ. (China)

Published in SPIE Proceedings Vol. 3863:
1999 International Conference on Biomedical Optics
Qingming Luo; Britton Chance; Lihong V. Wang; Steven L. Jacques, Editor(s)

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