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Proceedings Paper

Transillumination of breast phantoms using diffuse photon-density waves
Author(s): Laure Montandon-Varoda; Daniel Salzmann; Frederic P. Bevilacqua; Christian D. Depeursinge
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Paper Abstract

Diffuse Photon Density Waves (DPDWs) characterise photon migration through diffusive media in the frequency-domain. Theoretically, we describe DPDWs propagation using the diffraction theory based on the diffusion approximation to the transport equation. Experimentally, we study the propagation of 100 MHz-modulated DPDWs through (optical)-breast-like phantoms. The great interest of probing these phantoms lies in the fact that they contain very small optical inhomogeneities, with a diameter of 5 mm only and with inhomogeneitj^ackground absorption and scattering contrasts of 1.1,1.5,2.0 and 4.0 respectively. We show that both most contrasted inhomogeneities (in absorption and scattering) can be distinguished, while the 1.5 contrasted one is visible only in scattering. This is consistent with the measured actual accuracy of our set-up which is 0.3% in amplitude and 0.15¡ in phase. Experimental results are compared to simulations, time-domain experimental results and X-ray measurements.

Paper Details

Date Published: 15 July 1999
PDF: 5 pages
Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); doi: 10.1117/12.356850
Show Author Affiliations
Laure Montandon-Varoda, Ecole Polytechnique Federale de Lausanne (Switzerland)
Daniel Salzmann, Ecole Polytechnique Federale de Lausanne (Switzerland)
Frederic P. Bevilacqua, Ecole Polytechnique Federale de Lausanne (United States)
Christian D. Depeursinge, Ecole Polytechnique Federale de Lausanne (Switzerland)

Published in SPIE Proceedings Vol. 3597:
Optical Tomography and Spectroscopy of Tissue III
Britton Chance; Robert R. Alfano; Bruce J. Tromberg, Editor(s)

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