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Proceedings Paper

Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography
Author(s): Yici Guo; Howard E. Savage; Feng Liu; Stimson P. Schantz M.D.; Peng Pei Ho; Robert R. Alfano
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Paper Abstract

Second harmonic imaging was used to evaluate the subsurface layer structure of hamster cheek pouch mucosal tissues using femtosecond laser technology. Two dimensional images of hamster cheek pouch mucosa were obtained by scanning the second harmonic signal at various lateral and axial positions. The spatial mapping of the second harmonic signals showed depth differentiation between different tissue layers.

Paper Details

Date Published: 15 July 1999
PDF: 3 pages
Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); doi: 10.1117/12.356846
Show Author Affiliations
Yici Guo, CUNY/City College (United States)
Howard E. Savage, The New York Eye and Ear Infirmary (United States)
Feng Liu, CUNY/City College (United States)
Stimson P. Schantz M.D., The New York Eye and Ear Infirmary (United States)
Peng Pei Ho, CUNY/City College (United States)
Robert R. Alfano, CUNY/City College (United States)

Published in SPIE Proceedings Vol. 3597:
Optical Tomography and Spectroscopy of Tissue III
Britton Chance; Robert R. Alfano; Bruce J. Tromberg, Editor(s)

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