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Proceedings Paper

Intravenous volume tomographic pulmonary angiography imaging
Author(s): Ruola Ning; John G. Strang; Biao Chen; David L. Conover; Rongfeng Yu
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Paper Abstract

This study presents a new intravenous (IV) tomographic angiography imaging technique, called intravenous volume tomographic digital angiography (VTDA) for cross sectional pulmonary angiography. While the advantages of IV-VTDA over spiral CT in terms of volume scanning time and resolution have been validated and reported in our previous papers for head and neck vascular imaging, the superiority of IV-VTDA over spiral CT for cross sectional pulmonary angiography has not been explored yet. The purpose of this study is to demonstrate the advantage of isotropic resolution of IV-VTDA in the x, y and z directions through phantom and animal studies, and to explore its clinical application for detecting clots in pulmonary angiography. A prototype image intensifier-based VTDA imaging system has been designed and constructed by modifying a GE 8800 CT scanner. This system was used for a series of phantom and dog studies. A pulmonary vascular phantom was designed and constructed. The phantom was scanned using the prototype VTDA system for direct 3D reconstruction. Then the same phantom was scanned using a GE CT/i spiral CT scanner using the routine pulmonary CT angiography protocols. IV contrast injection and volume scanning protocols were developed during the dog studies. Both VTDA reconstructed images and spiral CT images of the specially designed phantom were analyzed and compared. The detectability of simulated vessels and clots was assessed as the function of iodine concentration levels, oriented angles, and diameters of the vessels and clots. A set of 3D VTDA reconstruction images of dog pulmonary arteries was obtained with different IV injection rates and isotropic resolution in the x, y and z directions. The results of clot detection studies in dog pulmonary arteries have also been shown. This study presents a new tomographic IV angiography imaging technique for cross sectional pulmonary angiography. The results of phantom and animal studies indicate that IV-VTDA is superior to spiral CT for cross sectional pulmonary angiography.

Paper Details

Date Published: 20 May 1999
PDF: 12 pages
Proc. SPIE 3660, Medical Imaging 1999: Physiology and Function from Multidimensional Images, (20 May 1999); doi: 10.1117/12.349587
Show Author Affiliations
Ruola Ning, Univ. of Rochester (United States)
John G. Strang, Univ. of Rochester (United States)
Biao Chen, Univ. of Rochester (United States)
David L. Conover, Univ. of Rochester (United States)
Rongfeng Yu, Univ. of Rochester (United States)

Published in SPIE Proceedings Vol. 3660:
Medical Imaging 1999: Physiology and Function from Multidimensional Images
Chin-Tu Chen; Anne V. Clough, Editor(s)

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