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Proceedings Paper

Analysis of pharmaceutical materials through the use of FT-Raman microprobe imaging
Author(s): Christiane Rodriguez
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Paper Abstract

The characterization of pharmaceutical solids has always ben a concern for the pharmaceutical scientist, whether it be a formulator, analytical chemist or process chemist. Traditionally, characterization meant chemical purity, but today a more comprehensive characterization is crucial for a safe and consistent pharmaceutical product. Typically, FTIR and FT-Raman are the vibrational techniques used to physical characterize solids. Recent advances in imaging technology have made FT-Raman microscopy another powerful tool for obtaining information of pharmaceutical products. This advance has made it possible to not only obtain chemical information, but gives the ability to spatially resolve the obtained information. Descriptions of various experimental procedures for analyzing formulated tablets as well as other materials of pharmaceutical interest using imaging techniques will be given.

Paper Details

Date Published: 9 April 1999
PDF: 7 pages
Proc. SPIE 3608, Biomedical Applications of Raman Spectroscopy, (9 April 1999); doi: 10.1117/12.345412
Show Author Affiliations
Christiane Rodriguez, Nicolet Instrument Corp. (United States)

Published in SPIE Proceedings Vol. 3608:
Biomedical Applications of Raman Spectroscopy
Michael D. Morris, Editor(s)

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