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Proceedings Paper

Absorption measurements using low-coherence interferometry
Author(s): Trude Storen; Dan Ostling; Lars Othar Svaasand; Ole Johan Lokberg; Tore Lindmo
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Paper Abstract

The basic use of low coherence interferometry is measuring the intensity of light reflected from defined depths in a partially transparent object. The light back-scattered from a certain depth in the object carries information about the medium through which it has passed. Absorption and scattering attenuate the intensity of the light, and will thus reduce the interference signal from a given depth. One single interference measurement will not discriminate between attenuation due to absorption and scattering. However, by measuring the interference signal at several different wavelengths, discrimination between the two parameters is possible, if they vary differently with wavelength. Especially when measurements are performed in a wavelength region where the scattering coefficient is constant, measurements at two different wavelengths will give the difference in absorption at the two wavelengths. We present preliminary measurements on scattering and absorbing solutions showing a qualitative difference in absorption measured at 810 and 830 nm. As an absorbing solution we used a commercially available dye with an absorption maximum at 800 nm while intralipid was used to introduce scattering. The aim of the work is to measure the oxygenation saturation of blood through absorption measurements at different wavelengths using low coherence interferometry.

Paper Details

Date Published: 12 February 1999
PDF: 9 pages
Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); doi: 10.1117/12.339178
Show Author Affiliations
Trude Storen, Norwegian Univ. of Science and Technology (Norway)
Dan Ostling, SINTEF (Norway)
Lars Othar Svaasand, Norwegian Univ. of Science and Technology (Norway)
Ole Johan Lokberg, Norwegian Univ. of Science and Technology (Norway)
Tore Lindmo, Norwegian Univ. of Science and Technology (Norway)

Published in SPIE Proceedings Vol. 3567:
Optical and Imaging Techniques for Biomonitoring IV
Marco Dal Fante; Hans-Jochen Foth; Neville Krasner M.D.; Renato Marchesini; Halina Podbielska M.D., Editor(s)

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