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Proceedings Paper

Time-resolved transmittance for the noninvasive determination of tissue optical properties
Author(s): Sergio De Nicola; Maria Daniela Falco; Maria Lepore
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Paper Abstract

Time-resolved measurements of femtosecond light pulses transmitted through turbid biological media were performed to determine the optical absorption and scattering coefficients. A simple model based on the time-dependent diffusion equation allows us to calculate analytical expressions for the spatially-integrated time-resolved transmittance in terms of the interaction coefficients of the tissue slab. We derived the optical coefficients by fitting the diffusion solution to the experimental data of the spatially integrated time-resolved diffuse transmittance for different boundary conditions at the turbid medium-air interface.

Paper Details

Date Published: 15 January 1999
PDF: 10 pages
Proc. SPIE 3570, Biomedical Sensors, Fibers, and Optical Delivery Systems, (15 January 1999); doi: 10.1117/12.336942
Show Author Affiliations
Sergio De Nicola, INFM, Univ. degli Studi di Napoli Federico II, and Istituto di Cibernetica (Italy)
Maria Daniela Falco, INFM, Univ. degli Studi di Napoli Federico II, and Istituto di Cibernetica (Italy)
Maria Lepore, INFM, Univ. degli Studi di Napoli Federico II, and Istituto di Cibernetica (Italy)


Published in SPIE Proceedings Vol. 3570:
Biomedical Sensors, Fibers, and Optical Delivery Systems
Francesco Baldini; Nathan I. Croitoru; Martin Frenz; Ingemar Lundstroem; Mitsunobu Miyagi; Riccardo Pratesi; Otto S. Wolfbeis, Editor(s)

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