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Proceedings Paper

Simple instrument for the characterization of diffuse reflectance
Author(s): Mario E. Giardini; Laura Loconte; Giovanni Guido Guizzetti; Andrea Gelmetti; Paolo Lago
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Paper Abstract

An apparatus for the measurement of the radial dependence of the continuous-wave diffuse reflectance of a tissue is described. It consists in a probe, which is applied on the tissue, and a detection unit. By employing an array of incoherent semiconductor light sources (LED's) and continuous- wave detection, probe structure is considerably simpler than other devices described in literature, allowing moreover an efficient coupling of the emitted light towards the tissue. The high responsivity so obtained permits fast and accurate measurements. Measurement speed, probe compactness and accuracy are potentially sufficient for the in-vivo application of the method to surgically exposed tissue. A preliminary set of data, measured on a scattering phantom and on non-exposed in-vivo tissue, is presented. Even though available models fitted to the measured data give the correct order of magnitude for light transport coefficients, in order to extract reliable absolute values they should be corrected for probe nonidealities. The availability of extensive high- quality in-vivo data is to this regard stimulating for further theoretical investigations.

Paper Details

Date Published: 19 January 1999
PDF: 5 pages
Proc. SPIE 3568, Optical Biopsies and Microscopic Techniques III, (19 January 1999); doi: 10.1117/12.336818
Show Author Affiliations
Mario E. Giardini, Clinica Policlinoco S. Matteo/INFM (Italy)
Laura Loconte, Univ. degli Studi di Milano (Italy)
Giovanni Guido Guizzetti, Univ. degli Studi di Pavia (Italy)
Andrea Gelmetti, Policlinico S. Matteo (Italy)
Paolo Lago, Policlinico S. Matteo (Italy)

Published in SPIE Proceedings Vol. 3568:
Optical Biopsies and Microscopic Techniques III
Irving J. Bigio; Herbert Schneckenburger; Jan Slavik; Katarina Svanberg M.D.; Pierre M. Viallet, Editor(s)

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