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Proceedings Paper

Monte Carlo prediction of mean-time photon measurement density functions
Author(s): Muneo Ono; Eiji Okada
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Paper Abstract

The scattering of tissue causes the ambiguity of volume of tissue interrogated by near infrared spectroscopy (NIRS) instruments. The sampling volume, which is the volume of tissue interrogated by NIRS instrument with CW light, can be predicted by calculating the distribution of light which arrives the detector. Recently, time-resolved and frequency modulated measurements has been applied to near-infrared spectroscopy instruments. Although the volume of tissue interrogated by the measurements of mean time, phase and so forth may be different from that by CW intensity measurement, there are very few studies on the volume of tissue interrogated by time-resolved and frequency domain measurements. In this study a Monte Carlo algorithm to predict the volume of tissue interrogated by mean time measurements is proposed and is applied to homogeneous and layered models. The volume of tissue interrogated by mean time measurement is significantly different from the sampling volume.

Paper Details

Date Published: 30 December 1998
PDF: 8 pages
Proc. SPIE 3566, Photon Propagation in Tissues IV, (30 December 1998); doi: 10.1117/12.334367
Show Author Affiliations
Muneo Ono, Keio Univ. (Japan)
Eiji Okada, Keio Univ. (Japan)

Published in SPIE Proceedings Vol. 3566:
Photon Propagation in Tissues IV
David A. Benaron M.D.; Britton Chance; Marco Ferrari; Matthias Kohl-Bareis, Editor(s)

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