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Proceedings Paper

Episodes of apnea and bradycardia in the preterm newborn: impact on cerebral oxygenation measured by near-infrared spectrophotometry
Author(s): Sabine Van Huffel; Johan Craemers; Bart Lenaerts; Hans Daniels; Gunnar Naulaers; Paul Casaer
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Paper Abstract

The objective of this study is to evaluate the effect of episodes of apneas and/or mild bradycardia (heart rate decreases of 10 to 20% or more) on cerebral oxyhemoglobin (HbO2) and reduced hemoglobin (Hb) concentration as measured by Near Infrared Spectrophotometry (NIRS). Measurements were carried out on 7 preterm infants who experienced apneic and bradycardiac events. It is shown how to characterize these events using time-frequency analysis. In addition to NIRS (performed with a NIRO-500 from Hamamatsu, Japan), the heart rate, ECG, peripheral arterial oxygen saturation (measured at the foot) and respiration (abdominal and thoracic pressure, and nasal airflow) were continuously recorded. The impact of apneic events and periodic breathing on these measurements reveals the clinical relevance of NIRS. In particular, we investigate whether these changes in heart rate and respiration also influence HbO2 and reduced Hb concentration in neonatal brain. These changes are characterized, as well as their relationships with the other simultaneously recorded signals such as peripheral arterial oxygen saturation.

Paper Details

Date Published: 30 December 1998
PDF: 12 pages
Proc. SPIE 3566, Photon Propagation in Tissues IV, (30 December 1998); doi: 10.1117/12.334358
Show Author Affiliations
Sabine Van Huffel, Katholieke Univ. Leuven (Belgium)
Johan Craemers, Katholieke Univ. Leuven (Belgium)
Bart Lenaerts, Katholieke Univ. Leuven (Belgium)
Hans Daniels, Univ. Hospital Gasthuisberg (Belgium)
Gunnar Naulaers, Univ. Hospital Gasthuisberg (Belgium)
Paul Casaer, Univ. Hospital Gasthuisberg (Belgium)

Published in SPIE Proceedings Vol. 3566:
Photon Propagation in Tissues IV
David A. Benaron M.D.; Britton Chance; Marco Ferrari; Matthias Kohl-Bareis, Editor(s)

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