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Proceedings Paper

Statistical methods for 3D reconstruction of viruses using cryo electron microscopy data
Author(s): Wen Gao; Peter C. Doerschuk
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Paper Abstract

Cryo electron microscopy of viruses provides 2D projections of the scattering intensity of the viral particle but the orientation of the projections is not known. We describe an approach to reconstructing the 3D scattering intensity in spite of the unknown projection orientations using nonlinear least squares ideas where the reconstruction is guaranteed to have the icosahedral symmetry known to be present in the viral particle.

Paper Details

Date Published: 22 September 1998
PDF: 9 pages
Proc. SPIE 3459, Bayesian Inference for Inverse Problems, (22 September 1998); doi: 10.1117/12.323797
Show Author Affiliations
Wen Gao, Purdue Univ. (United States)
Peter C. Doerschuk, Purdue Univ. (United States)

Published in SPIE Proceedings Vol. 3459:
Bayesian Inference for Inverse Problems
Ali Mohammad-Djafari, Editor(s)

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