A novel algorithm is demonstrated to determine the reduced scattering and absorption coefficients from time-resolved reflectance measurements at two positions on the surface of biotissue. The algorithm is very straightforward and fast, in which only some simple mathematical operations are involved, avoiding complicated iterative non-linear fitting to the time- resolved curve. The derived reduced scattering coefficient is not affected by whatever boundary condition is applied. The algorithm was verified using the time-resolved data from the Monte-Carlo model. Both the semi-infinite medium and the turbid slab medium were tested. In contrast to the non-linear fitting method, it is found using this algorithm that both the scattering and absorption coefficients can be determined to a high accuracy.

Date Published: 13 May 1998
PDF: 6 pages
Proc. SPIE 3254, Laser-Tissue Interaction IX, (13 May 1998); doi: 10.1117/12.308182

Published in SPIE Proceedings Vol. 3254:
Laser-Tissue Interaction IX
Steven L. Jacques; Jeff Lotz, Editor(s)