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Proceedings Paper

Effects of temperature on the near-infrared spectroscopic measurement of glucose
Author(s): Byungjo Jung; Michael J. McShane; Sohi Rastegar; Gerard L. Cote
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Paper Abstract

The noninvasive monitoring of sugars, and in particular, glucose using near-IR (NIR) spectroscopy would be useful for a number of applications including regulating the nutrients in cell culture medium, monitoring on-line processes in the food industry, and in vivo monitoring for control of glucose in DIabetic patients. The focus of this research was the investigation of the temperature effects across a 10.6 to 40.4 degrees C range on Fourier filtered and unfiltered single-beam as well as absorbance glucose and water NIR spectra. It is known that the positions of water absorption bands centered at 1.923 and 2.623 micrometers depend heavily on temperature effects while the glucose bands are temperature insensitive across this range. The water absorption bands were shown to shift to lower wavelengths while the distance between these bands increased with increasing temperatures. Partial least squares (PLS) calibration models were constructed at five separate temperatures, 15.7, 20.5, 25.5, 35.6, and 40.4 degrees C. When absorbance spectra were used with reference scans taken at the same temperature and PLS models were used, no significant difference in the standard error of prediction (SEP) was noted with temperature. Using PLS calibration with single-beam spectra at one temperature showed large SEPs at the other temperatures. The use of Fourier filtered single-beam spectra reduced the SEP but still showed an increase as large temperature differences were produced and the filtered single beam approach did not reduce the SEP to the level achieved with the absorbance spectra.

Paper Details

Date Published: 1 May 1998
PDF: 6 pages
Proc. SPIE 3253, Biomedical Sensing and Imaging Technologies, (1 May 1998); doi: 10.1117/12.308048
Show Author Affiliations
Byungjo Jung, Texas A&M Univ. (United States)
Michael J. McShane, Texas A&M Univ. (United States)
Sohi Rastegar, Texas A&M Univ. (United States)
Gerard L. Cote, Texas A&M Univ. (United States)

Published in SPIE Proceedings Vol. 3253:
Biomedical Sensing and Imaging Technologies
Robert A. Lieberman; Tuan Vo-Dinh, Editor(s)

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