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Proceedings Paper

Determination of optical properties by variation of boundary conditions
Author(s): Stephan Nickell; Matthias Essenpreis; U. Kraemer; Matthias Kohl-Bareis; Dirk Boecker M.D.
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Paper Abstract

Propagation of photons in multiple scattering media depends on absorbing and scattering properties as well as the boundary conditions of the semi-infinite medium. A new method is shown that makes use of differences in boundary conditions to determine the optical properties. Induced are these different conditions by varying the reflectivity of a sensor head. We describe the influence of the change in reflectivity with the common diffusion theory. By building a ratio between the spatially-resolved diffuse reflectance under different boundary conditions it is possible to calculate the optical properties of homogeneous phantoms. Due to optical heterogeneities in living tissue, limitations of the method was observed, which restricts the application to in vivo measurements.

Paper Details

Date Published: 1 January 1998
PDF: 8 pages
Proc. SPIE 3194, Photon Propagation in Tissues III, (1 January 1998); doi: 10.1117/12.301062
Show Author Affiliations
Stephan Nickell, Boehringer Mannheim GmbH (Germany)
Matthias Essenpreis, Boehringer Mannheim GmbH (Germany)
U. Kraemer, Boehringer Mannheim GmbH (Germany)
Matthias Kohl-Bareis, Humboldt-Univ. zu Berlin (Germany)
Dirk Boecker M.D., Boehringer Mannheim GmbH (Germany)

Published in SPIE Proceedings Vol. 3194:
Photon Propagation in Tissues III
David A. Benaron M.D.; Britton Chance; Marco Ferrari, Editor(s)

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