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Proceedings Paper

Two-dimensional birefringence imaging in biological tissue using polarization-sensitive optical coherence tomography
Author(s): Johannes F. de Boer; Thomas E. Milner; Martin J. C. van Gemert; J. Stuart Nelson M.D.
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Paper Abstract

Using a polarization sensitive Michelson interferometer, we measure 2D images of optical birefringence in bovine tendon as a function of depth with a technique known as optical coherence tomography (OCT). Detection of the polarization state of the signal, formed by interference of backscattered light from the sample and a mirror in the reference arm, gives the optical phase delay between light that has propagated along the fast and slow axes of the birefringent tendon. Images showing the change in birefringence in response to laser irradiation are presented. The technique allows rapid non-contact investigation of tissue structural properties through 2D imaging of birefringence.

Paper Details

Date Published: 13 January 1998
PDF: 6 pages
Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, (13 January 1998); doi: 10.1117/12.297943
Show Author Affiliations
Johannes F. de Boer, Univ. of California/Irvine (United States)
Thomas E. Milner, Univ. of California/Irvine (United States)
Martin J. C. van Gemert, Academic Medical Ctr. (Netherlands)
J. Stuart Nelson M.D., Univ. of California/Irvine (United States)

Published in SPIE Proceedings Vol. 3196:
Optical and Imaging Techniques for Biomonitoring III
Hans-Jochen Foth; Renato Marchesini; Halina Podbielska M.D.; Abraham Katzir, Editor(s)

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