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Proceedings Paper

Effects of nitric oxide and its synthesis inhibitor on neuron efficiency detected by a fiber-optic-based multisensor
Author(s): Zheng Shen; Jun Hua; Shuzhi Lin; Xiangfeng Liu
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Paper Abstract

Sodium nitroprusside (SNP) as an exogenous nitric oxide (NO) donor and N(omega) -nitro-L-arginine methyl ester(L-NAME) as NO synthesis inhibitor was driven into monkey cortex by iontophoresis, their effects on face recognition of monkey were observed, and neuron firing as well as neuron efficiency were monitored by fiberoptic-based multisensor during face recognition. The results show that L-NAME and low dose of SNP(5 nM) did not have any significant effect on face recognition and neuron efficiency, however high dose of SNP(50 nM) increased simultaneously both correct rate of face recognition and neuron efficiency, but not neuron firing. The results were discussed according to NO and its synthesis mechanism.

Paper Details

Date Published: 13 January 1998
PDF: 7 pages
Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, (13 January 1998); doi: 10.1117/12.297927
Show Author Affiliations
Zheng Shen, Peking Univ. (China)
Jun Hua, Peking Univ. (China)
Shuzhi Lin, Peking Univ. (China)
Xiangfeng Liu, Peking Univ. (China)

Published in SPIE Proceedings Vol. 3196:
Optical and Imaging Techniques for Biomonitoring III
Hans-Jochen Foth; Renato Marchesini; Halina Podbielska M.D.; Abraham Katzir, Editor(s)

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