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Proceedings Paper

Evaluation of early rheumatic disorders in PIP joints using a cw-transillumination method: first clinical results
Author(s): Viravuth Prapavat; Till Luhmann; Andreas Krause; Marina Backhaus; Juergen Beuthan; Gerhard J. Mueller
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Paper Abstract

This paper presents first clinical results of an in vivo experimental study on the detection of early pathological changes of rheumatoid arthritis (RA) using a near IR cw- transillumination method on finger joints (PIP). The inflammation of a joint system when caused by RA leads to changes in the synovial membrane and synovial. Measurements have shown that these rheumatic induced processes results in a variation in optical properties within the joint system. Using a cw system the PIP-joint is transilluminated with diode lasers at the articular cavity in order to use the entire scattered distribution of the transmitted radiation intensity for diagnostic purposes. The study includes results of in vivo measurements on 24 joints with known status and the evaluation of the feasibility of different distribution properties for detection of early RA.

Paper Details

Date Published: 13 January 1998
PDF: 8 pages
Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, (13 January 1998); doi: 10.1117/12.297919
Show Author Affiliations
Viravuth Prapavat, Laser- und Medizin-Technologie gGmbH (Germany)
Till Luhmann, Universitaetsklinikum Benjamin Franklin der Freien Univ. Berlin (Germany)
Andreas Krause, Universitaetsklinikum Charite der Humboldt-Univ. zu Berlin (Germany)
Marina Backhaus, UniversiUniversitaetsklinikum Charite der Humboldt-Univ. zu Berlin (Germany)
Juergen Beuthan, Universitaetsklinikum Benjamin Franklin der Freien Univ. Berlin (Germany)
Gerhard J. Mueller, Laser- und Medizin-Technologie gGmbH and Universitaetsklinikum Benjamin Franklin der Freie (Germany)

Published in SPIE Proceedings Vol. 3196:
Optical and Imaging Techniques for Biomonitoring III
Hans-Jochen Foth; Renato Marchesini; Halina Podbielska M.D.; Abraham Katzir, Editor(s)

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