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Proceedings Paper

Diode-laser ablation therapy for submucosal gastric cancer using indocyanine-green solution injection to the submucosa
Author(s): Takuya Hayashi; Tsunenori Arai; Shigeki Tokonabe; Harumi Itoh; Makoto Kikuchi; Shoryoku Hino; Katsunori Masuda; Hiroaki Suzuki; Hisao Tajiri; Kunihiko Hino; Yashiroh Nogami
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Paper Abstract

A 805-nm diode laser ablation therapy with indocyanine green (ICG) was studied for the endoscopic treatment of early gastric cancer. The ICG solution with 1mg/ml was administrated to the submucosa of the resected porcine and anesthetized canine stomach for the purpose of enhancing the tissue absorption to the laser light. We established complete removal of the mucosa and the submucosa with laser power of 12 or 25 watts. The proper muscle was intact because the ICG solution prevents the laser light penetration to the proper muscle. An ablated depth could be easily recognized by observing the ablated surface color. Our results showed that the combination of the 805 nm diode laser irradiation and the submucosal injection of the ICG solution might provide selective and controllable endoscopic treatment for early gastric cancer.

Paper Details

Date Published: 16 June 1997
PDF: 7 pages
Proc. SPIE 2975, Laser-Tissue Interaction VIII, (16 June 1997); doi: 10.1117/12.275505
Show Author Affiliations
Takuya Hayashi, National Defense Medical College (Japan)
Tsunenori Arai, National Defense Medical College (Japan)
Shigeki Tokonabe, National Defense Medical College (Japan)
Harumi Itoh, National Defense Medical College (Japan)
Makoto Kikuchi, National Defense Medical College (Japan)
Shoryoku Hino, Jikei Univ. School of Medicine (Japan)
Katsunori Masuda, Jikei Univ. School of Medicine (Japan)
Hiroaki Suzuki, Jikei Univ. School of Medicine (Japan)
Hisao Tajiri, National Cancer Ctr. Hospital East (Japan)
Kunihiko Hino, National Defense Medical College (Japan)
Yashiroh Nogami, Self-Defense Central Hospital (Japan)

Published in SPIE Proceedings Vol. 2975:
Laser-Tissue Interaction VIII
Steven L. Jacques, Editor(s)

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