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Proceedings Paper

Design of low-energy neutron beams for boron neutron capture synovectomy
Author(s): Jacquelyn C. Yanch; Ruth E. Shefer; E. Binello
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Paper Abstract

A novel application of the 10B(n, (alpha) )7Li nuclear reaction for the treatment of rheumatoid arthritis is under development. this application, called Boron Neutron Capture Synovectomy (BNCS), is briefly described here and the differences between BNCS and Boron Neutron Capture Therapy (BNCT) are discussed in detail. These differences lead to substantially altered demands on neutron beam design for each therapy application. In this paper the considerations for neutron beam design for the treatment of arthritic joints via BNCS are discussed, and comparisons with the design requirements for BNCT are made. This is followed by a description of potential moderator/reflector assemblies that are calculated to produce intense, high- quality neutron beams based on the 7Li(p,n) accelerator- based reactions. Total therapy time and therapeutic ratios are given as a function of both moderator length and boron concentration. Finally, a means of carrying out multi- directional irradiations of arthritic joints is proposed.

Paper Details

Date Published: 27 February 1997
PDF: 10 pages
Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); doi: 10.1117/12.267911
Show Author Affiliations
Jacquelyn C. Yanch, Massachusetts Institute of Technology (United States)
Ruth E. Shefer, Newton Scientific Inc. (United States)
E. Binello, Massachusetts Institute of Technology (United States)

Published in SPIE Proceedings Vol. 2867:
International Conference Neutrons in Research and Industry
George Vourvopoulos, Editor(s)

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