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Proceedings Paper

Medium- and low-volatile organic compounds generated by laser tissue interaction
Author(s): Martin Spleiss; Lothar W. Weber
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Paper Abstract

Different tissue samples have been irradiated with surgical XeCl- and CO2-lasers. The generated laser plume was sampled and analyzed concerning medium and low volatile organic compounds. Differences in the composition of the pyrolysis products in dependance of tissues and lasers are presented. Quantification of aromatic hydrocarbons was carried out. It is obvious that the ratios between the single aromatic hydrocarbons gave hints at the temperatures of the laser tissue interaction process. Some aromatic hydrocarbons were typical high temperature products like phenylacetylene, whereas toluene could be found at lower temperatures with comparable high concentration. Two special classes of compounds, presumed by Curie point pyrolysis of proteins and not yet verified by synthesis, were identified in the aerosol of the CO2-laser. Probably five different amino acids might be the precursors of these compounds whereas by Curie point pyrolysis only three amino acids were reported as precursors. The particular debris which was sampled separately on glass fiber filters was extracted with different solvents. Several compounds absorbed at the particles could be identified and will be discussed. In the polar acetone extract some of main compounds remained unknown. A special clean-up procedure for polycyclic aromatic hydrocarbons (PAH) was carried out. Qualitative and quantitative results of the PAH analysis are presented. The results are compared with the results of other working groups.

Paper Details

Date Published: 5 December 1996
PDF: 10 pages
Proc. SPIE 2923, Laser-Tissue Interaction and Tissue Optics II, (5 December 1996); doi: 10.1117/12.260738
Show Author Affiliations
Martin Spleiss, Institut fuer Arbeits- und Sozialmedizin/Univ. Ulm (Germany)
Lothar W. Weber, Institut fuer Arbeits- und Sozialmedizin/Univ. Ulm (Germany)

Published in SPIE Proceedings Vol. 2923:
Laser-Tissue Interaction and Tissue Optics II
Hansjoerg Albrecht; Guy P. Delacretaz; Thomas H. Meier; Rudolf W. Steiner; Lars Othar Svaasand, Editor(s)

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